Medication-Related Osteonecrosis of the Jaw Associated with Palatal Bone and Soft Tissue Trauma: A Case Report
Singh Harpreet, Saleh Wafaa, 차승희, Katz Joseph, Ruprecht Axel,
소속 상세정보
( Singh Harpreet ) - University of Florida College of Dentistry Department of Oral and Maxillofacial Diagnostic Sciences
( Saleh Wafaa ) - University of Florida College of Dentistry Department of Oral and Maxillofacial Diagnostic Sciences
차승희 ( Cha Seung-Hee ) - University of Florida College of Dentistry Department of Oral and Maxillofacial Diagnostic Sciences
( Katz Joseph ) - University of Florida College of Dentistry Department of Oral and Maxillofacial Diagnostic Sciences
( Ruprecht Axel ) - University of Florida College of Dentistry Department of Oral and Maxillofacial Diagnostic Sciences, Oral and Maxillofacial Radiology
Abstract
The aim of this case report is to present a case of 68-year-old male with a history of multiple myeloma and the intravenous use of Zometa (zoledronic acid) who had developed medication-related osteonecrosis of the jaw (MRONJ) following a hot pizza burn to the palate. Clinical and radiographic findings revealed grade 1 MRONJ of the right side of the hard palate. Soft tissue trauma and delayed epithelialization may be associated with some cases of MRONJ. Patients on anti-resorptive medications or anti-angiogenic drugs should be informed of the risk of bone exposure and subsequent MRONJ secondary to physical/chemical insults to the bone and soft tissue in the oral cavity.
키워드
Bisphosphonates; Medication related osteonecrosis of the jaw; Osteonecrosis; Zoledronic acid
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